Opened the box, plugged into a Mac Pro 2019, fired up Cubase 10.5 and all worked fine. You will need to order a separate Thunderbolt2 cable and Thunderbolt 3 adatper (for MacPro 2019) b/c Steinberg skimped on the cable (~$50 extra cost from Apple or other vendor). Also, check to make sure the installed firmware version as shipped from the factory is compatible with the AXR4 App Utility - i had to do a quick firmware update to get full functionality - it's not really clear (hidden text at the bottom of the page) on the Cubase driver download page. Also, 1st time I ordered from SamAsh. Package was sent quickly, packaged well and a good deal. Will consider SamAsh again for online order.