Its noticeable differences are in the bass (compared to what your computer might offer you) it has at least ten times more detail than the simulation. Deadmau5 uses this type of machines to get the real sound you hear at the raves. Professional DJs wouldnt settle for anything less than true analog. I have met many artists who have spent thousands on modular gear who were very impressed with the performance and results from phatty, Thankyou Dr. moog. Its monophonic which means it only plays one note at a time.